Given these considerations, antipsychotic drugs should be prescribed in a manner that is most likely to minimize the occurrence of tardive dyskinesia. Chronic antipsychotic treatment should generally be reserved for patients who suffer from a chronic illness that 1) is known to respond to antipsychotic drugs, and 2) for whom alternative, equally effective, but potentially less harmful treatments are not available or appropriate. In patients who do require chronic treatment, the smallest dose and the shortest duration of treatment producing a satisfactory clinical response should be sought. The need for continued treatment should be reassessed periodically.
Drug has few CV adverse effects and may be preferred in patients with cardiac disease.
Dose of 2 mg is therapeutic equivalent of 100 mg chlorpromazine.
When changing from tablets to decanoate injection, patient should initially receive 10 to 20 times the oral dose once monthly (not more than 100 mg).
Assess patient periodically for extrapyramidal reactions and tardive dyskinesia.
Don’t withdraw drug abruptly except when required, because abrupt withdrawal may cause severe adverse reaction. Taper dosage over several weeks.
Safety and efficacy of drug injection in children haven’t been established, and oral drug isn’t recommended for children younger than age 3.
Drug is especially useful for agitation related to senile dementia. Tardive dyskinesia may occur more often, especially in elderly women.
Elderly patients usually need lower initial doses and a more gradual dosage adjustment.
Haloperidol is used to relieve the symptoms of schizophrenia and other problems which affect the way you think, feel or behave. These problems may make you hear, see or sense things that are not there, or believe things that are not true, or feel unusually suspicious. If you are taking haloperidol for these reasons, you may be prescribed tablets or capsules to take for a short while to get your symptoms under control, and then a long-acting, or 'depot', injection may be recommended for you. There is a separate medicine leaflet called Haloperidol long-acting injection which gives more information about this.