Even those not willing to fully acquit saturated fat from the role of CV villain accept that carbohydrate consumption should be moderated. Studies like MESA and EPIC, which have shown worse metabolic and CV outcomes with higher blood levels of even-chain SFAs, implicate carbs because plasma levels of even-chain SFAs correlate more strongly with drivers of de-novo lipogenesis, including alcohol, soft drinks, and potatoes, than with dietary sources such as meat, butter, or cheese. ……………..Among the most touted is the Mediterranean dietary pattern, which is rich in fruit, vegetables, whole grains, fatty fish, lean meat, oils, nuts, and legumes. There are supporting data for this eating pattern, including the PREDIMED trial, in which 7447 men and women free of CV disease but at high CV risk were randomly assigned to 1 of 2 Mediterranean diet groups (supplemented with either olive oil or nuts) or to a low-fat control diet. The primary endpoint of myocardial infarction, stroke, or CV death was reduced by 30% compared with the control group, largely driven by an early reduction in stroke.