The gallbladder is a small digestive organ whose primary function is to store bile created by the liver. Sometimes the gallbladder fails to work properly, and can become filled with gallstones. Gallbladder disease is more common in women, overweight people, people with gastro-intestinal problems and those with high blood cholesterol levels. There is a genetic component, as well. Gallstones are the primary cause of gallbladder disease; however, two uncommon causes are gallbladder cancer and gallbladder attack, or Cholecystitis. Identifying the symptoms of and seeking treatment for gallbladder disease can help you avoid discomfort and medical complications.