Abnormal GH levels can usually be modified once the causes are identified. Synthetic GH is available to alleviate deficiencies in children (treatment of adults with GHD is more controversial). Combinations of surgery, medication, and radiation can be used to treat pituitary tumors that are causing excess GH production. The important thing is to identify GH abnormalities as soon as possible for good outcomes. If left untreated, a child with GH deficiency will continue to have a short stature compared to peers. Likewise, the bone growth changes associated with gigantism and acromegaly are permanent.
For those who want to avoid estrogens in any form, phytoestrogens from plants are a consideration. A soy extract that provides at least 50 mg of soy phytoestrogens are often a key ingredient for effective natural estrogen replacement therapy. Based upon records of dietary soy consumption inJapan, where breast cancer incidence is very low, daily soy isoflavone intake has been estimated at 50 mg per day. The typical Western diet, on the other hand, only provides 1 to 5 mg a day of the soy isoflavones that may protect against several forms of cancer.
Thyroxine and triiodothyronine can be measured as free thyroxine and free triiodothyronine , which are indicators of thyroxine and triiodothyronine activities in the body. They can also be measured as total thyroxine and total triiodothyronine , which also depend on the thyroxine and triiodothyronine that is bound to thyroxine-binding globulin . A related parameter is the free thyroxine index , which is total thyroxine multiplied by thyroid hormone uptake , which, in turn, is a measure of the unbound thyroxine-binding globulins.  Additionally, thyroid disorders can be detected prenatally using advanced imaging techniques and testing fetal hormone levels.